Placement & Removal Procedure
EndoBarrier is a thin, flexible tube-shaped liner that works by creating a physical barrier between food and a portion of the intestinal wall. The liner prevents the interaction of food with enzymes and hormones in the proximal intestine. In effect, food bypasses the duodenum, but without surgery. Clinical data suggest that EndoBarrier Therapy works by affecting key hormones involved in insulin sensitivity, glucose metabolism, satiety and food intake. It delivers its full therapeutic effect directly to target organs, unlike pharmaceuticals that get diluted in the bloodstream.1 It should be noted that animal studies suggest that glycemic changes and weight loss are not associated with malabsorption.2
1. de Jonge C., et al, Endoscopic Duodenal-Jejunal Bypass Liner Rapidly Improves Type 2 Diabetes.’, Obesity Surgery, Sept. 2013, Volume 23, Issue 9, pp 1354-1360. 2. Munoz, R., et. al., “Isolated Duodenal Exclusion Increases Energy Expenditure in Diet-induced Obese Rats.” Am J. Physio., September 12, 2012.