A Single, Transformative solution

EndoBarrier Therapy is an adjunctive treatment option for type 2 diabetes and obesity. It redefines the treatment paradigm for patients . . .

    • For whom lifestyle changes and oral diabetes medications are no longer effective
    • Who want to avoid the progression to injectable therapies
    • For whom surgery is considered a step too far and a therapy of last resort
    • At risk for serious health consequences

Procedure:

View the video to the right to learn more about EndoBarrier Placement & Removal

Placement & Removal Procedure

EndoBarrier is a thin, flexible tube-shaped liner that works by creating a physical barrier between food and a portion of the intestinal wall. The liner prevents the interaction of food with enzymes and hormones in the proximal intestine. In effect, food bypasses the duodenum, but without surgery. Clinical data suggest that EndoBarrier Therapy works by affecting key hormones involved in insulin sensitivity, glucose metabolism, satiety and food intake. It delivers its full therapeutic effect directly to target organs, unlike pharmaceuticals that get diluted in the bloodstream.1 It should be noted that animal studies suggest that glycemic changes and weight loss are not associated with malabsorption.2

1. de Jonge C., et al, Endoscopic Duodenal-Jejunal Bypass Liner Rapidly Improves Type 2 Diabetes.’, Obesity Surgery, Sept. 2013, Volume 23, Issue 9, pp 1354-1360. 2. Munoz, R., et. al., “Isolated Duodenal Exclusion Increases Energy Expenditure in Diet-induced Obese Rats.” Am J. Physio., September 12, 2012.

Therapy Comparisons

Increases in the number of medications and changes in dose can lead to compliance issues and side-effects.

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Compelling Clinical Results

In addition to the clinical results shown in the Efficacy section (link) of this website, EndoBarrier Therapy has been shown to show many life changing improvements

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The Role of Specialists

Successful results with EndoBarrier® Therapy are best achieved through a care approach involving diabetes management, psychological evaluation, nutritional and behavioral counseling, exercise guidance, a specially-trained endoscopy team and the patient’s primary care physician.

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Devices bridge the gap between medication that is not fulfilling its promise and surgery that is not desirable to many patients. Medical devices, used in combination with medications, can drive patients into a much better metabolic state.

Carel le Roux MRCP, PhD, FRCP Consultant in Metabolic Medicine Professor University College Dublin, Ireland

Clinical Effects

Restore healthy glycemic levels.

Produce significant weight loss.

Potentially improve CV risk factors.
.

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Referring Physicians

See a list of Centers that currently offer EndoBarrier Therapy.

Referring Physician

See a list of Centers that currently offer EndoBarrier Therapy.

News Meetings & Events

Learn more about EndoBarrier Therapy at these upcoming professional meetings and events.

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The Multidisciplinary Team

Successful results with EndoBarrier Therapy are best achieved through a care approach involving diabetes management, psychological evaluation, nutritional and behavioural counseling, exercise guidance, a specially-trained endoscopy team and the patient’s primary care physician.

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Find a Treatment Center

Learn more about this treatment for type 2 diabetes and/or obesity by contacting an EndoBarrier Therapy near your practice.

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Therapy Effects

Clinical data suggest that EndoBarrier Therapy works by affecting key hormones involved in insulin sensitivity, glucose metabolism, satiety and food intake.

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EndoBarrier Patient Profile

EndoBarrier Therapy is an adjunctive treatment option for type 2 diabetes and obesity. Clinically proven to lower glucose levels and significantly reduce weight, without using medication or surgery to achieve its effect, EndoBarrier Therapy may be the answer for a broad cohort of your current patient population

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Success Stories

Learn more about how our patients met the challenge of type 2 diabetes and excess weight